Covid-19 Vaccine and the Risk Involved in the Vaccine PICO Question: In patients

Covid-19 Vaccine and the Risk Involved in the Vaccine
PICO Question: In patients aged 65 and older (P), how does the use of the Covid-19 vaccine (I) compared to not receiving the vaccine (C) influence the risk of developing adverse reaction (O) within the first week of administration?
Introduction
The research proposal should:
Start with a statement of the problem and objective for the study, which articulates the main objectives that the study desires to achieve.
Include a description of the theoretical framework to be utilized and a rationale for choosing a framework.
Describe the significance and relevance of the problem. Why is this particular study needed? How will findings contribute to the field of advanced practice nursing? Why is this research needed?
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